Since 2003, the President’s Emergency Plan for AIDS Relief (PEPFAR) has provided billions of US tax dollars to expand HIV treatment, care, and prevention programs, mostly in sub-Saharan Africa. According to the Institute of Medicine, PEPFAR’s $54 billion authorization from 2003-2013 constitutes the “largest global health initiative focused on a single disease ever undertaken.” PEPFAR has generated significant health gains, sharply reducing HIV-related and all-cause mortality. Read more.